TargetMol

AKR1C2 Protein, Human, Recombinant (His)

Product Code:
 
TAR-TMPY-03497
Product Group:
 
Recombinant Proteins
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-TMPY-03497-50ug50ugEnquire
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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  • Further Information
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Further Information

Bioactivity:
AKR1C2 is a member of the aldo/keto reductase superfamily, which consists of more than 4 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. AKR1C2 gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 1p15-p14. Three transcript variants encoding two different isoforms have been found for AKR1C2 gene.
Molecular Weight:
38.6 kDa (predicted)
Purity:
98%

References

1.Jin Y. et al., 2011, Biochem J. 437 (1): 53-61. 2.Veilleux A. et al., 2012, Am J Physiol Endocrinol Metab. 302 (8): E941-9. 3.Kuang P. et al., 2012, Lung Cancer. 77 (2): 427-32.