TargetMol

UBA6 Protein, Human, Recombinant (GST)

Product Code:
 
TAR-TMPY-06748
Product Group:
 
Recombinant Proteins
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-TMPY-06748-500ug500ugEnquire
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
UBA6 (Ubiquitin Like Modifier Activating Enzyme 6) is a Protein Coding gene. The UBA6 gene, located on 4q13.2, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog. Uba6 is a homolog of the ubiquitin-activating enzyme, Uba1, and activates two ubiquitin-like proteins (UBLs), ubiquitin and FAT10. UBA6 is an alternative enzyme for ubiquitin activation in vertebrates that plays a pivotal role in early mouse development. UBA6 is widely expressed in the lymph node, appendix, and other tissues. Diseases associated with UBA6 include Ichthyosis, Congenital, Autosomal Recessive 4A, and Johanson-Blizzard Syndrome. Among its related pathways are the Metabolism of proteins and the Innate Immune System.
Molecular Weight:
143.56 kDa (predicted)
Purity:
98%

References

1.Kim MJ,et al.(2019) Early-stage paired housing improves social interaction in neuronal uba6-deficient mice. Biochem Biophys Res Commun 514 (2): 545-549. 2.Gavin JM,et al.(2012) Mechanistic studies on activation of ubiquitin and di-ubiquitin-like protein, fat10, by ubiquitin-like modifier activating enzyme 6, uba6. J Biol Chem 287 (19): 15512-15522. 3.Chen Z,et al.(2020) Down-regulation of uba6 exacerbates brain injury by inhibiting the activation of notch signaling pathway to promote cerebral cell apoptosis in rat acute cerebral infarction model. Mol Cell Probes 53 101612.