TargetMol

Artemin Protein, Human, Recombinant (hFc)

Product Code:
 
TAR-TMPK-00109
Product Group:
 
Recombinant Proteins
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-TMPK-00109-100ug100ugEnquire
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TAR-TMPK-00109-1mg1mgEnquire
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TAR-TMPK-00109-500ug500ugEnquire
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
Artemin (ARTN) is a member of glial cell line-derived neurotrophic factor (GDNF) family of ligands, and its signaling is mediated via a multi-component receptor complex including the glycosylphosphatidylinositol-anchored GDNF family receptors a (GFRa1, GFRa3) and RET receptor tyrosine kinase. The major mechanism of ARTN action is via binding to a non-signaling co-receptor. The major function of ARTN is to drive the molecule to induce migration and axonal projection from sympathetic neurons.
Molecular Weight:
39.3 kDa (predicted). Due to glycosylation, the protein migrates to 48-52 kDa based on Tris-Bis PAGE result.
Purity:
98%

References

1.Hezam K, et al. Artemin promotes oncogenicity, metastasis and drug resistance in cancer cells. Rev Neurosci. 2018 Jan 26;29(1):93-98. doi: 10.1515/revneuro-2017-0029. PMID: 28937965.