TargetMol

CD28 Protein, Human/Cynomolgus/Rhesus macaque, Recombinant (His & Avi)

Product Code:
 
TAR-TMPK-00110
Product Group:
 
Recombinant Proteins
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1

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TAR-TMPK-00110-100ug100ugEnquire
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Further Information

Bioactivity:
CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells. CD28 Protein, Human/Cynomolgus/Rhesus macaque, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 18.2 kDa and the accession number is P10747-1.
Molecular Weight:
18.2 kDa (predicted). Due to glycosylation, the protein migrates to 36-52 kDa based on Tris-Bis PAGE result.
Purity:
98%

References

1.Suntharalingam G, et al. Cytokine Storm in a Phase 1 Trial of the Anti-CD28 Monoclonal Antibody TGN1412[J]. New England Journal of Medicine, 2006, 355(10):1018-1028.