TargetMol

GM-CSFR alpha Protein, Human, Recombinant (His & Avi), Biotinylated

Product Code:
 
TAR-TMPK-00254
Product Group:
 
Recombinant Proteins
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-TMPK-00254-100ug100ugEnquire
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TAR-TMPK-00254-1mg1mgEnquire
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TAR-TMPK-00254-500ug500ugEnquire
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Further Information

Bioactivity:
In the first trimester, the GM-CSF-R was found to be present on villous cytotrophoblast and all populations of extravillous trophoblast. Expression by villous syncytiotrophoblast was weak or absent, but this increased markedly by term. GM-CSF-R were also expressed by fetal Hofbauer cells within the mesenchyme of the chorionic villi and by uterine glandular epithelium and decidual macrophages within maternal decidua. GM-CSFR alpha Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 37.7 kDa and the accession number is P15509-1.
Molecular Weight:
37.7 kDa (predicted). Due to glycosylation, the protein migrates to 68-75 kDa based on Tris-Bis PAGE result.
Purity:
98%

References

1.Jokhi PP, et al. Demonstration of the low affinity alpha subunit of the granulocyte-macrophage colony-stimulating factor receptor (GM-CSF-R alpha) on human trophoblast and uterine cells. J Reprod Immunol. 1994 Mar;26(2):147-64. doi: 10.1016/0165-0378(94)90037-x. PMID: 7932390.