TargetMol

HER2/ErbB2 Protein, Human, Recombinant (His & Avi)

Product Code:
 
TAR-TMPK-00428
Product Group:
 
Recombinant Proteins
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
❮❯

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CodeSizePrice
TAR-TMPK-00428-100ug100ugEnquire
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-TMPK-00428-1mg1mgEnquire
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Quantity:
TAR-TMPK-00428-500ug500ugEnquire
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
ErbB2, also called Neu and Her2 (human epidermal growth factor receptor 2), is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors. ErbB family members serve as receptors for the epidermal growth factor (EGF) family of growth factors.Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane.
Molecular Weight:
72.3 kDa (predicted). Due to glycosylation, the protein migrates to 80-100 kDa based on Tris-Bis PAGE result.
Purity:
98%

References

1.Tagliabue E, et al. HER2 as a target for breast cancer therapy[J]. EXPERT OPINION ON BIOLOGICAL THERAPY, 2010, 10(5):711-724.