TargetMol

HER4/ERBB4 Protein, Human, Recombinant (His & Avi)

Product Code:
 
TAR-TMPK-00448
Product Group:
 
Recombinant Proteins
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-TMPK-00448-100ug100ugEnquire
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TAR-TMPK-00448-1mg1mgEnquire
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TAR-TMPK-00448-500ug500ugEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
Her4, a member of the EGF receptor family, plays a variety of roles in physiological and pathological states. Genetic studies have indicated a link between Her4 and type 2 diabetes and obesity. Her4 may play an important role in glucose homeostasis and lipogenesis. Her4 deficiency-related obesity and adipose tissue inflammation may contribute to the development of MetS. HER4/ERBB4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 72.7 kDa and the accession number is Q15303-1.
Molecular Weight:
72.7 kDa (predicted). Due to glycosylation, the protein migrates to 80-110 kDa based on Tris-Bis PAGE result.
Purity:
98%

References

1.Zeng F, et al. Her4 deletion predisposes to development of metabolic syndrome in mice. Am J Physiol Endocrinol Metab. 2018 Oct 1;315(4):E583-E593. doi: 10.1152/ajpendo.00166.2018. Epub 2018 Jun 26. PMID: 29944391; PMCID: PMC6230712.