TargetMol

Complement Factor D/CFD Protein, Rhesus macaque, Recombinant (His)

Product Code:
 
TAR-TMPK-00671
Product Group:
 
Recombinant Proteins
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-TMPK-00671-100ug100ugEnquire
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TAR-TMPK-00671-1mg1mgEnquire
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TAR-TMPK-00671-500ug500ugEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium. Complement Factor D/CFD Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 25.7 kDa and the accession number is H9EXC1-1.
Molecular Weight:
25.7 kDa (predicted). Due to glycosylation, the protein migrates to 26-30 kDa based on Tris-Bis PAGE result.
Purity:
98%

References

1.Abrera-Abeleda MA, et al. Mesangial immune complex glomerulonephritis due to complement factor D deficiency. Kidney Int. 2007 Jun;71(11):1142-7. doi: 10.1038/sj.ki.5002235. Epub 2007 Apr 4. PMID: 17410102.