TargetMol

TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (hFc)

Product Code:
 
TAR-TMPK-00708
Product Group:
 
Recombinant Proteins
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
❮❯

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TAR-TMPK-00708-100ug100ugEnquire
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TAR-TMPK-00708-1mg1mgEnquire
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TAR-TMPK-00708-500ug500ugEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) induces apoptosis selectively via its interaction with the death receptors TRAILR1/DR4 and TRAILR2/DR5 in a wide range of cancers, while sparing normal cells. Despite its tremendous potential for cancer therapeutics, the translation of TRAIL into the clinic has been confounded by TRAIL-resistant cancer populations.
Molecular Weight:
48.8 kDa (predicted). Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.
Purity:
98%

References

1.Deng D, Shah K. TRAIL of Hope Meeting Resistance in Cancer. Trends Cancer. 2020 Dec;6(12):989-100 doi: 10.1016/j.trecan.2020.06.006. Epub 2020 Jul 24. PMID: 32718904; PMCID: PMC7688478.