TargetMol

RANK/TNFRSF11A Protein, Mouse, Recombinant (hFc)

Product Code:
 
TAR-TMPK-00723
Product Group:
 
Recombinant Proteins
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1

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TAR-TMPK-00723-100ug100ugEnquire
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TAR-TMPK-00723-1mg1mgEnquire
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TAR-TMPK-00723-500ug500ugEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
TNFRSF11A, also known as receptor activator of NF-κB (RANK), activates several signaling pathways, such as NF-κB, JNK, ERK, p38α, and Akt/PKB. RANK/TNFRSF11A is a novel and frequent target for de novo methylation in gliomas, which affects apoptotic activity and focus formation thereby contributing to the molecular pathogenesis of gliomas. RANK/TNFRSF11A Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 47.0 kDa and the accession number is O35305.
Molecular Weight:
47.0 kDa (predicted). Due to glycosylation, the protein migrates to 57-67 kDa based on Tris-Bis PAGE result.
Purity:
98%

References

1.von dem Knesebeck A, et al. RANK (TNFRSF11A) is epigenetically inactivated and induces apoptosis in gliomas. Neoplasia. 2012 Jun;14(6):526-34. doi: 10.1596/neo.12360. PMID: 22787434; PMCID: PMC3394195.