TargetMol

IL-22RA1 Protein, Mouse, Recombinant (hFc)

Product Code:
 
TAR-TMPK-01071
Product Group:
 
Recombinant Proteins
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-TMPK-01071-100ug100ugEnquire
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TAR-TMPK-01071-1mg1mgEnquire
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TAR-TMPK-01071-500ug500ugEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
Interleukin (IL)-22 is a member of the IL-10 family of cytokines and represents an important effector molecule of activated Th22, Th1, and Th17 cells, as well as Tc-cell subsets, gammadelta T cells, natural killer (NK), and NKT cells. IL-22 mediates its effects via a heterodimeric transmembrane receptor complex consisting of IL-22R1 and IL-10R2 and subsequent Janus kinase-signal transducers and activators of transcription (JAK-STAT) signaling pathways including Jak1, Tyk2, and STAT3. IL-22RA1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 51.1 kDa and the accession number is Q80XZ4.
Molecular Weight:
51.1 kDa (predicted). Due to glycosylation, the protein migrates to 65-68 kDa based on Tris-Bis PAGE result.
Purity:
98%

References

1.Wolk K, et al. Biology of interleukin-22. Semin Immunopathol. 2010 Mar;32(1):17-3doi: 10.1007/s00281-009-0188-x. Epub 2010 Feb 2. PMID: 20127093.