TargetMol

Glypican 2/GPC2 Protein, Mouse, Recombinant (His)

Product Code:
 
TAR-TMPK-01081
Product Group:
 
Recombinant Proteins
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-TMPK-01081-100ug100ugEnquire
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-TMPK-01081-1mg1mgEnquire
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TAR-TMPK-01081-500ug500ugEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
Glypicans can function as coreceptors for multiple signaling molecules known for regulating cell growth, motility, and differentiation. Some members of the glypican family, including glypican 2 (GPC2) and glypican 3 (GPC3), are expressed in childhood cancers and liver cancers, respectively. Antibody-based therapies targeting glypicans are being investigated in preclinical and clinical studies, with the goal of treating solid tumors that do not respond to standard therapies.
Molecular Weight:
59.9 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 32-35 kDa based on Tris-Bis PAGE result.
Purity:
98%

References

1.Li N, et al. Glypicans as Cancer Therapeutic Targets. Trends Cancer. 2018 Nov;4(11):741-754. doi: 10.1016/j.trecan.2018.09.004. Epub 2018 Sep 28. PMID: 30352677; PMCID: PMC6209326.