TargetMol

ASPH Protein, Mouse, Recombinant (His)

Product Code:
 
TAR-TMPK-01083
Product Group:
 
Recombinant Proteins
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-TMPK-01083-100ug100ugEnquire
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-TMPK-01083-1mg1mgEnquire
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TAR-TMPK-01083-500ug500ugEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
Aspartate β-hydroxylase (ASPH) is silent in normal adult tissues only to re-emerge during oncogenesis where its function is required for generation and maintenance of malignant phenotypes. Exosomes enable prooncogenic secretome delivering and trafficking for long-distance cell-to-cell communication.Expression profiling of Notch signaling components positively correlates with ASPH expression in breast cancer patients, confirming that ASPH-Notch axis acts functionally in breast tumorigenesis. ASPH Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 49.4 kDa and the accession number is Q8BSY0-1.
Molecular Weight:
49.4 kDa (predicted) same as Tris-Bis PAGE result.
Purity:
98%

References

1.Lin Q, et al. ASPH-notch Axis guided Exosomal delivery of Prometastatic Secretome renders breast Cancer multi-organ metastasis. Mol Cancer. 2019 Nov 7;18(1):156. doi: 10.1186/s12943-019-1077-0. PMID: 31694640; PMCID: PMC6836474.