TargetMol

PODXL2 Protein, Mouse, Recombinant (His)

Product Code:
 
TAR-TMPK-01088
Product Group:
 
Recombinant Proteins
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-TMPK-01088-100ug100ugEnquire
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TAR-TMPK-01088-1mg1mgEnquire
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TAR-TMPK-01088-500ug500ugEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
Transmembrane protein endoglycan (PODXL2), which belongs to the CD34-family of highly glycosylated sialomucins. Endoglycan is broadly expressed in the developing mouse brains and is proteolytically shed in vitro in mouse neurons and in vivo in mouse brains. Endoglycan shedding in primary neurons was mediated by the transmembrane protease a disintegrin and metalloprotease 10 (ADAM10), but not by its homolog ADAM17. PODXL2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 51.7 kDa and the accession number is Q8CAE9.
Molecular Weight:
51.7 kDa (predicted). Due to glycosylation, the protein migrates to 80-110 kDa based on Tris-Bis PAGE result.
Purity:
98%

References

1.Hsia HE, et al. Endoglycan (PODXL2) is proteolytically processed by ADAM10 (a disintegrin and metalloprotease 10) and controls neurite branching in primary neurons. FASEB J. 2021 Sep;35(9):e21813. doi: 10.1096/fj.202100475R. PMID: 34390512.