TargetMol

FcRH5/FcRL5 Protein, Human, Recombinant (His & Avi), Biotinylated

Product Code:
 
TAR-TMPK-01145
Product Group:
 
Recombinant Proteins
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-TMPK-01145-100ug100ugEnquire
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Further Information

Bioactivity:
FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. FcRH5/FcRL5 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 94.19 kDa and the accession number is Q96RD9-1.
Molecular Weight:
94.19 kDa (predicted). Due to glycosylation, the protein migrates to 90-130 kDa based on Tris-Bis PAGE result.
Purity:
98%

References

1.Elkins K, et al. FcRL5 as a target of antibody-drug conjugates for the treatment of multiple myeloma. Mol Cancer Ther. 2012;11(10):2222-2232. doi:10.1158/1535-7163.MCT-12-0087.