TargetMol

Beta Klotho Protein, Mouse, Recombinant (His)

Product Code:
 
TAR-TMPK-01150
Product Group:
 
Recombinant Proteins
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-TMPK-01150-100ug100ug£481.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-TMPK-01150-500ug500ug£1,709.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-TMPK-01150-1mg1mg£2,809.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
Beta-klotho (KLB) is a coreceptor required for endocrine fibroblast growth factor (FGF) 15/19 and FGF21 signaling in the brain. Klb is prominent within the hypothalamus, which is consistent with its metabolic functions, but diverse roles for Klb are now emerging. Central Klb expression is low but discrete and may govern FGF-targeted sites. Beta Klotho Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 109.91 kDa and the accession number is Q99N32-1.
Molecular Weight:
109.91 kDa (predicted). Due to glycosylation, the protein migrates to 120-130 kDa based on Tris-Bis PAGE result.
Purity:
98%

References

1.Bono BS, et al. Spatial distribution of beta-klotho mRNA in the mouse hypothalamus, hippocampal region, subiculum, and amygdala. J Comp Neurol. 2022 Feb 10. doi: 10.1002/cne.25306. Epub ahead of print. PMID: 35143049.