TargetMol

LAMP5 Protein, Mouse, Recombinant (hFc)

Product Code:
 
TAR-TMPK-01161
Product Group:
 
Recombinant Proteins
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1

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TAR-TMPK-01161-100ug100ugEnquire
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TAR-TMPK-01161-1mg1mgEnquire
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TAR-TMPK-01161-500ug500ugEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
Lysosome-associated membrane protein 5 (LAMP5) is a mammalian ortholog of the Caenorhabditis elegans protein, UNC-46, which functions as a sorting factor to localize the vesicular GABA transporter UNC-47 to synaptic vesicles. LAMP5 deficiency led to a larger intensity-dependent increase of wave I, II and V peak amplitude of auditory brainstem response. LAMP5 plays a pivotal role in sensorimotor processing in the brainstem and spinal cord. LAMP5 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 50 kDa and the accession number is Q9D387.
Molecular Weight:
50 kDa (predicted). Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
Purity:
98%

References

1.Koebis M, et al. LAMP5 in presynaptic inhibitory terminals in the hindbrain and spinal cord: a role in startle response and auditory processing. Mol Brain. 2019 Mar 12;12(1):20. doi: 10.1186/s13041-019-0437-4. PMID: 30867010; PMCID: PMC6416879.