TargetMol

LOX-1 Protein, Mouse, Recombinant (His)

Product Code:
 
TAR-TMPK-01168
Product Group:
 
Recombinant Proteins
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-TMPK-01168-100ug100ugEnquire
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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TAR-TMPK-01168-1mg1mgEnquire
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TAR-TMPK-01168-500ug500ugEnquire
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This product comes from: United States.
Typical lead time: 10-14 working days.
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  • Further Information
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Further Information

Bioactivity:
LOX-1 is a transmembrane glycoprotein that binds to and internalizes ox-LDL.LOX-1 gene deletion in mice and anti-LOX-1 therapy has been shown to decrease inflammation, oxidative stress and atherosclerosis. LOX-1 deletion also results in damage from ischemia, making LOX-1 a promising target of therapy for atherosclerosis and related disorders. In this article we focus on the different mechanisms for regulation, signaling and the various effects of LOX-1 in contributing to atherosclerosis.
Molecular Weight:
36.1 kDa (predicted). Due to glycosylation, the protein migrates to 55-63 kDa based on Tris-Bis PAGE result.
Purity:
98%

References

1.Kattoor AJ, et al. LOX-1: Regulation, Signaling and Its Role in Atherosclerosis. Antioxidants (Basel). 2019 Jul 11;8(7):218. doi: 10.3390/antiox8070218. PMID: 31336709; PMCID: PMC6680802.