TargetMol

Hepcidin/HAMP Protein, Mouse, Recombinant (GST)

Product Code:
 
TAR-TMPK-01170
Product Group:
 
Recombinant Proteins
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
❮❯

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CodeSizePrice
TAR-TMPK-01170-100ug100ugEnquire
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-TMPK-01170-1mg1mgEnquire
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-TMPK-01170-500ug500ugEnquire
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This product comes from: United States.
Typical lead time: 10-14 working days.
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  • Further Information
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Further Information

Bioactivity:
Hepcidin, the main regulator of iron metabolism, is synthesized and released by hepatocytes in response to increased body iron concentration and inflammation. Deregulation of hepcidin expression is a common feature of genetic and acquired iron disorders: in Hereditary Hemochromatosis (HH) and iron-loading anemias low hepcidin causes iron overload, while in Iron Refractory Iron Deficiency Anemia (IRIDA) and anemia of inflammation (AI), high hepcidin levels induce iron-restricted erythropoiesis.
Molecular Weight:
29.05 kDa (predicted) same as Tris-Bis PAGE result.
Purity:
98%

References

1.Silvestri L, et al. Hepcidin and the BMP-SMAD pathway: An unexpected liaison. Vitam Horm. 2019;110:71-99. doi: 10.1016/bs.vh.2019.01.004. Epub 2019 Feb 10. PMID: 30798817.