TargetMol

MESDC2 Protein, Human, Recombinant (His)

Product Code:
 
TAR-TMPY-01451
Product Group:
 
Recombinant Proteins
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-TMPY-01451-100ug100ugEnquire
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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  • Further Information
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Further Information

Bioactivity:
MESD (Mesoderm Development LRP Chaperone) is a Protein Coding gene. LDLR chaperone MESD, also known as Mesoderm development protein, Mesoderm development candidate 2, Renal carcinoma antigen NY-REN-61, and MESDC2, is a member of the MESD family. It is widely expressed in the thyroid, placenta, and other tissues. MESDC2 is a chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). The LDLR maturation activity resides in the N- and C-terminal unstructured regions. MESDC2 acts as a modulator of the Wnt pathway since some LDLRs are coreceptors for the canonical Wnt pathway. MESDC2 is essential for the specification of embryonic polarity and mesoderm induction.
Molecular Weight:
23.6 kDa (predicted)
Purity:
98%

References

1.Scanlan M.J. et al., 1999, Int. J. Cancer 83:456-464. 2.Veltman,IM. et al.,2005, Hum Mol Genet??14?(14):1955-63. 3.Koduri V. et al., 2007, Biochemistry 46:6570-7.