TargetMol

CREB3L1 Protein, Human, Recombinant (aa 396-519, His)

Product Code:
 
TAR-TMPY-03627
Product Group:
 
Recombinant Proteins
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-TMPY-03627-100ug100ugEnquire
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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  • Further Information
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Further Information

Bioactivity:
CREB3L1, also known as OASIS, is a cellular transcription factor synthesized as a membrane-bound precursor. It is a putative endoplasmic reticulum (ER) stress sensor in astrocytes with a mechanism of activation. OASIS mRNA expression was detected in pancreatic β-cell lines and rodent islets, and the expression level was up-regulated by ER stress-inducing compounds. CREB3L1 may have a role in pancreas development. CREB3L1 may also play an important role in limiting virus spread by inhibiting proliferation of virus-infected cells. In vitro, CREB3L1 binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE. It may play a role in gliosis.
Molecular Weight:
15.2 kDa (predicted)
Purity:
98%

References

1.Denard B. et al., 2011, Cell Host Microbe. 10 (1): 65-74. 2.Debelenko LV. et al., 2011, 50 (12): 1054-62. 3.Vellanki. et al., 2010, Endocrinology. 151 (9): 4146.