TargetMol

SARS-CoV-2 NSP10 Protein (His)

Product Code:
 
TAR-TMPY-06011
Product Group:
 
Recombinant Proteins
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-TMPY-06011-100ug100ugEnquire
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Further Information

Bioactivity:
NSP10 is a major regulator of coronavirus replicase function. NSP10 contains two zinc fingers and binds and stimulates both NSP14 and NSP16 activities. Researchers has found that the nsp10 surface that interacts with nsp14 and nsp16 and possibly other subunits of the viral replication complex may be a target for the development of antiviral compounds against pathogenic coronaviruses. SARS-CoV-2 NSP10 Protein (His) is expressed in E. coli expression system. The predicted molecular weight is 15.7 kDa and the accession number is YP_009725306.1.
Molecular Weight:
15.7 kDa (predicted)
Purity:
98%

References

1.Micka?l Bouvet,et al.Coronavirus Nsp10, a Critical Co-factor for Activation of Multiple Replicative Enzymes.THE JOURNAL OF BIOLOGICAL CHEMISTRY.2014Yuanyuan Ma,et al.Structural basis and functional analysis of the SARS coronavirus nsp14-nsp10 complex. Proc Natl Acad Sci USA. 2015Etienne Decroly,et al.Crystal structure and functional analysis of the SARS-coronavirus RNA cap 2'-O-methyltransferase nsp10/nsp16 complex. PLoS Pathog.2011