AdipoGen Life Sciences

anti-Vaspin (human), mAb (VP63)

Product Code:
 
AG-20A-0045
Product Group:
 
Primary Antibodies
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1κ
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
VP63
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Shipping:
 
Blue Ice
Storage:
 
-20°C
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Immunohistochemical staining of vaspin with anti-Vaspin (human), mAb (VP63) (AG-20A-0045) in psoriatic skin lesions (A). Negative control for vaspin in psoriatic skin lesions (B). Blue hematoxylin stained cell nuclei.
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Immunohistochemical staining of vaspin with anti-Vaspin (human), mAb (VP63) (AG-20A-0045) in psoriatic skin lesions (A). Negative control for vaspin in psoriatic skin lesions (B). Blue hematoxylin stained cell nuclei.

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AG-20A-0045-C05050 ug£195.00
Quantity:
AG-20A-0045-C100100 ug£271.00
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Further Information

Alternate Names/Synonyms:
Visceral Adipose Tissue-derived Serine Protease Inhibitor; Serpin A12; OL-64
Concentration:
1mg/ml
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives.
Handling Advice:
After opening, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.
Immunogen:
Recombinant human vaspin.
Long Description:
Monoclonal Antibody. Recognizes human vaspin. Detects a band of ~48kDa by Western blot. Isotype: Mouse IgG1kappa. Clone: VP63. Applications: ELISA, IHC, WB. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. Vaspin (Visceral adipose tissue-derived serpin; Serpin A12), a serine protease inhibitor (serpin), is an insulin-sensitizing adipocytokine that has been isolated from both visceral and subcutaneous white adipose tissue. Based on recent findings, vaspin is suggested to regulate immune responses and inflammation and was found to be correlated with various metabolic parameters. Vaspin may represent a novel biomarker for obesity and impaired insulin sensitivity and might serve as a new therapeutic target of metabolic syndrome.
NCBI, Uniprot Number:
Q8IW75
Package Type:
Plastic Vial
Product Description:
Vaspin (Visceral adipose tissue-derived serpin; Serpin A12), a serine protease inhibitor (serpin), is an insulin-sensitizing adipocytokine that has been isolated from both visceral and subcutaneous white adipose tissue. Based on recent findings, vaspin is suggested to regulate immune responses and inflammation and was found to be correlated with various metabolic parameters. Vaspin may represent a novel biomarker for obesity and impaired insulin sensitivity and might serve as a new therapeutic target of metabolic syndrome.
Specificity:
Recognizes human vaspin. Detects a band of ~48kDa by Western blot.
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibodies
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C.

References

Central vaspin administration acutely reduces food intake and has sustained blood glucose-lowering effects: N. Kl?ting, et al.; Diabetologia 54, 1819 (2011) | Untersuchungen zur Rolle von Vaspin in der Psoriasis: K. Rall; Diss. Universit?t Leipzig (2012) (IHC protocol)