AdipoGen Life Sciences

anti-Jagged-1 (human) mAb (J1G53-3) (FITC)

Product Code:
 
AG-20A-0049F
Product Group:
 
Primary Antibodies
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1κ
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
J1G53-3
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Flow Cytometry
Shipping:
 
Blue Ice
Storage:
 
-20°C
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Flow cytometric analysis using anti-Jagged-1 (human), mAb (J1G53-3) (FITC) (Prod. No. AG-20A-0049F). A surface staining method was used to stain the normal human peripheral blood cells (CD4+ selections). An appropriate isotype control was used for FITC mo
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Flow cytometric analysis using anti-Jagged-1 (human), mAb (J1G53-3) (FITC) (Prod. No. AG-20A-0049F). A surface staining method was used to stain the normal human peripheral blood cells (CD4+ selections). An appropriate isotype control was used for FITC mo

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AG-20A-0049F-C05050 ug£227.00
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This product comes from: Switzerland.
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Further Information

Alternate Names/Synonyms:
Protein Jagged-1; CD339; JAG1
Concentration:
Lot dependent.
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives.
Handling Advice:
After opening, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.
Immunogen:
Recombinant human Jagged-1.
Labels - Conjugates:
FITC
Long Description:
Monoclonal Antibody. Recognizes human Jagged-1. Detects a band of ~180kDa by Western blot. Isotype: Mouse IgG1kappa. Clone: J1G53-3. Applications: FACS. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). Defects in Jagged-1 are the cause of Alagille syndrome type 1 (ALGS1) and tetralogy of Fallot (TOF).
NCBI, Uniprot Number:
P78504
Package Type:
Plastic Vial
Product Description:
Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). Defects in Jagged-1 are the cause of Alagille syndrome type 1 (ALGS1) and tetralogy of Fallot (TOF).
Specificity:
Recognizes human Jagged-1. Detects a band of ~180kDa by Western blot.
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibody Conjugates
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C.

References

Preclinical activity of the repurposed drug auranofin in classical Hodgkin lymphoma: M. Celegato, et al. Blood 126, 1394 (2015)