AdipoGen Life Sciences

anti-beta-Pix (mouse) pAb

Product Code:
 
AG-25A-0006
Product Group:
 
Primary Antibodies
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunocytochemistry (ICC)
  • Western Blot (WB)
Shipping:
 
-20°C
Storage:
 
-20°C
1 / 1
Western blot analysis using anti-beta-Pix (mouse), pAb (Prod. No. AG-25A-0006). 1: Mouse brain lysates (30?g). 2: NIH3T3 whole cell lysates (30?g). * beta-Pix is a major isoform in NIH3T3 lysates, while other beta-Pix
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Western blot analysis using anti-beta-Pix (mouse), pAb (Prod. No. AG-25A-0006). 1: Mouse brain lysates (30?g). 2: NIH3T3 whole cell lysates (30?g). * beta-Pix is a major isoform in NIH3T3 lysates, while other beta-Pix

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AG-25A-0006-C100100 ug£173.00
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This product comes from: Switzerland.
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Further Information

Alternate Names/Synonyms:
ARHGEF7; Rho Guanine Nucleotide Exchange Factor 7; PAK-interacting Exchange Factor beta; p85SPR; COOL-1
Concentration:
1mg/ml
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives.
Handling Advice:
After opening, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.
Immunogen:
Recombinant beta-Pix SH3 domain.
Long Description:
Polyclonal Antibody. Recognizes the multiple splice variants of human, mouse and rat beta-Pix a, b, bL, c and d-isoforms. Cross-reacts with human and rat beta-Pix. Source: Rabbit. Applications: ELISA, ICC, WB. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. beta-PIX acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. It interacts with PAK kinases through the SH3 domain. It may function as a positive regulator of apoptosis and is involved in cell migration. It is expressed with high levels in the central nervous system.
NCBI, Uniprot Number:
Q9ES28
Package Type:
Plastic Vial
Product Description:
beta-PIX acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. It interacts with PAK kinases through the SH3 domain. It may function as a positive regulator of apoptosis and is involved in cell migration. It is expressed with high levels in the central nervous system.
Source / Host:
Rabbit
Specificity:
Recognizes the multiple splice variants of human, mouse and rat beta-Pix a, b, bL, c and d-isoforms. Cross-reacts with human and rat beta-Pix.
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibodies
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 6 months after receipt when stored at -20°C.

References

Cloning of a SH3 domain-containing proline-rich protein, p85SPR, and its localization in focal adhesion: W.K. Oh, et al.; BBRC 235, 794 (1997) | betaPix-b(L), a novel isoform of betaPix, is generated by alternative translation: S. Rhee, et al.; BBRC 318, 415 (2004) | Enhanced cytotoxic effect of camptothecin nanosponges in anaplastic thyroid cancer cells in vitro and in vivo on orthotopic xenograft tumors: C.L. Gigliotti, et al.; Drug Deliv. 24, 670 (2017)