Bioviotica

Resistomycin

Product Code:
 
BVT-0036
Supplier:
 
Bioviotica
Regulatory Status:
 
RUO
Shipping:
 
20°C
Storage:
 
-20°C
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Chemical Structure
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Chemical Structure

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BVT-0036-M0011 mg£110.00
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Further Information

Alternate Names/Synonyms:
Geliomycin; Heliomycin; Itamycin; 3,5,7,10-Tetrahydroxy-1,1,9-trimethyl-1H-benzo-[cd]pyrene-2,6-dione
Appearance:
Yellow to orange solid.
CAS:
20004-62-0
EClass:
32160000
Form (Short):
solid
GHS Symbol:
GHS07,GHS08
Hazards:
H302, H312, H319, H351
InChi:
InChI=1S/C22H16O6/c1-7-4-9(23)15-18-13(7)10(24)5-8-14(18)19-16(20(15)27)11(25)6-12(26)17(19)21(28)22(8,2)3/h4-6,23-26H,1-3H3
InChiKey:
ABLACSIRCKEUOB-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 20004-62-0. Formula: C22H16O6. MW: 376.4. Isolated from Streptomyces sp. Antibacterial (Gram-positive and mycobacteria). RNA polymerase inhibitor. Apoptosis inducer.
MDL:
MFCD00597050
Molecular Formula:
C22H16O6
Molecular Weight:
376.4
Package Type:
Plastic Vial
Precautions:
P201, P270, P281, P301, P312, P302, P352, P405
Product Description:
Antibacterial (Gram-positive and mycobacteria) and antiviral. RNA polymerase inhibitor. Anticancer compound. Apoptosis inducer.
Purity:
>98% (HPLC)
Signal Word:
Warning
SMILES:
CC1=CC(O)=C2C(=O)C3=C4C(=C(O)C=C3O)C(=O)C(C)(C)C3=C4C2=C1C(O)=C3
Solubility Chemicals:
Soluble in DMSO or methanol.
Source / Host:
Isolated from Streptomyces sp.
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.

References

Effects of the antibiotic resistomycin on the synthesis of macromolecules: I. Haupt, et al.; Z. Allg. Mikrobiol. 156, 411 (1975) | 3-Alkanoyl-5-hydroxymethyl tetronic acid homologues and resistomycin: new inhibitors of HIV-1 protease. I. Fermentation, isolation and biological activity: B.E. Roggo, et al.; J. Antibiot. 47, 136 (1994) | Effects of polyphenolic anthrone derivatives, resistomycin and hypericin, on apoptosis in human megakaryoblastic leukemia CMK-7 cell line: Y. Shiono et al.; Z. Naturforsch. 57c, 923 (2002) | Assessment of resistomycin, as an anticancer compound isolated and characterized from Streptomyces aurantiacus AAA5: R. Vijayabharathi, et al.; J. Microbiol. 49, 920 (2011)