Ancell

anti-CD275 (human), mAb (ANC4E3)

Product Code:
 
ANC-263-020
Product Group:
 
Primary Antibodies
Supplier:
 
Ancell
Antibody Isotype:
 
Mouse IgG1 kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
ANC4E3
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
 
BI
Storage:
 
+4°C
 

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ANC-263-020-100ug100 ug£243.00
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This product comes from: Switzerland.
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Further Information

Alternate Names/Synonyms:
B7-H2; ICOS Ligand; B7-like Protein Gl50; B7RP-1
EClass:
32160000
Form (Short):
liquid
Formulation:
50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 0.5% Gentamicin sulfate
Handling Advice:
Avoid freeze/thaw cycles.
Immunogen:
Human Raji cells, recombinant human CD275-muIg.
Long Description:
Monoclonal Antibody. Isotype: Mouse IgG1kappa. Clone: ANC4E3. Applications: ELISA. 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 0.5% Gentamicin sulfate The inducible costimulator CD278 (ICOS) is similar to human CD28 (24% homology) and plays an analogous role in the T cell activation process. Signaling through CD278 is particularly important in progression of TH2 immune response. The receptor for human CD278 (ICOS) is CD275 (GL50), a member of the B7 family sharing ~20% homology with CD80 (B7-1) and CD86 (B7-2). Blockade of the CD278-CD275 interaction in mice improves allograft survival and reduces EAE.
Package Type:
Plastic Vial
Product Description:
The inducible costimulator CD278 (ICOS) is similar to human CD28 (24% homology) and plays an analogous role in the T cell activation process. Signaling through CD278 is particularly important in progression of TH2 immune response. The receptor for human CD278 (ICOS) is CD275 (GL50), a member of the B7 family sharing ~20% homology with CD80 (B7-1) and CD86 (B7-2). Blockade of the CD278-CD275 interaction in mice improves allograft survival and reduces EAE.
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibodies
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at +4°C.