IL-6 (mouse):Fc (mouse) (rec.) (non-lytic) MultiPack
Product Code:
CHI-MF-12006
CHI-MF-12006
Host Type:
Hamster
Hamster
Regulatory Status:
RUO
RUO
Target Species:
Mouse
Mouse
Shipping:
BI
BI
Storage:
-20°C
-20°C
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Code | Size | Price |
---|
CHI-MF-12006-C050 | 50 ug | £275.00 |
Quantity:
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This product comes from: Switzerland.
Typical lead time: 7-10 working days.
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Typical lead time: 7-10 working days.
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Further Information
Alternate Names/Synonyms:
Interleukin-6; B Cell Hybridoma Growth Factor; Interleukin HP-1
Biological Activity:
Shows the biological function of the IL-6 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain.
EClass:
32160000
Endotoxin:
<0.06EU/µg protein (LAL test; Lonza).
Form (Short):
liquid
Formulation:
Lyophilized from 0.2µm-filtered solution in PBS.
Handling Advice:
Avoid freeze/thaw cycles.Centrifuge lyophilized vial before opening and reconstitution.
Long Description:
Protein. The extracellular domain of mouse IL-6 (aa 1-211) is fused to the N-terminus of the Fc region of a mutant mouse IgG2a. Source: CHO cells. Endotoxin content: <0.06EU/µg protein (LAL test; Lonza). Lyophilized from 0.2µm-filtered solution in PBS. Purity: >98% (SDS-PAGE). Interleukin 6 (IL-6) is a pleiotropic alpha-helical cytokine that plays important roles in acute phase reactions, inflammation, hematopoiesis, bone metabolism and cancer progression. IL-6 activity is essential for the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. It is secreted by multiple cell types as a 22kDa-28kDa phosphorylated and variably glycosylated molecule. IL-6 induces signaling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6R) and a signal transducing subunit (gp130). IL-6 is a key factor for the growth of plasma cells.
NCBI, Uniprot Number:
NP_112445.1
Package Type:
Plastic Vial
Product Description:
Interleukin 6 (IL-6) is a pleiotropic alpha-helical cytokine that plays important roles in acute phase reactions, inflammation, hematopoiesis, bone metabolism and cancer progression. IL-6 activity is essential for the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. It is secreted by multiple cell types as a 22kDa-28kDa phosphorylated and variably glycosylated molecule. IL-6 induces signaling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6R) and a signal transducing subunit (gp130). IL-6 is a key factor for the growth of plasma cells.
Purity:
>98% (SDS-PAGE)
Sequence:
The extracellular domain of mouse IL-6 (aa 1-211) is fused to the N-terminus of the Fc region of a mutant mouse IgG2a.
Source / Host:
CHO cells
TAGs:
Fc
Transportation:
Non-hazardous
UNSPSC Category:
Interleukins
UNSPSC Number:
41116127
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Documents
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Product Name | Product Code | Supplier | IL-6 (human) (rec.) (His) | CHI-HF-20106 | Chimerigen | Summary Details | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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IL-6 (human):Fc (human) (rec.) MultiPack | CHI-HF-21006 | Chimerigen | Summary Details | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
IL-6 (human):Fc (human) (rec.) (non-lytic) MultiPack | CHI-HF-22006 | Chimerigen | Summary Details | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||