ProSci

Sin Nombre Virus Glycoprotein 1 Antibody

Product Code:
 
PSI-7681
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Application:
 
Enzyme-Linked Immunosorbent Assay (ELISA)
 

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CodeSizePrice
PSI-7681-0.02mg0.02mg£150.00
Quantity:
PSI-7681-0.1mg0.1mg£449.00
Quantity:
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Further Information

Additional Names:
Sin Nombre Virus Glycoprotein 1 Antibody:
Application Note:
Sin Nombre virus glycoprotein 1 antibody can detect 10ng Sin Nombre virus glycoprotein 1 peptide in ELISA at 1 μg/ml.
Background:
Sin Nombre virus (SNV) is a rodent-borne hantavirus of the family Bunyaviridae, an enveloped, negative-sense RNA viruses with a tripartite genome that can cause hantavirus pulmonary syndrome (HPS) (1). Hantavirus glycoprotein precursor (GPC) is posttranslationally cleaved into two glycoproteins G1 (Gn) and G2 (Gc). The G1 glycoprotein is is thought to be degraded by the host autophagy machinery, and this autophagic clearance is required for efficient virus repliaction (2).
Background References:
  • Spiropoulou CF, Morzunov S, Feldmann H, et al. Genome structure and variability of a virus causing hantavirus pulmonary syndrome. Virology 1994; 200:715-23.
  • Hussein ITM, Cheng E, Ganaie SS, et al. Autophagic clearance of Sin Nombre hanatavirus glycoprotein Gn promotes virus replication in cells. J. Virol. 2012; 86:7520-9.
Buffer:
Sin Nombre virus glycoprotein 1 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Sin Nombre virus glycoprotein 1 antibody was raised against a 19 amino acid peptide near the amino terminus of the Sin Nombre virus glycoprotein.

The immunogen is located within amino acids 60 - 110 of Sin Nombre Virus Glycoprotein 1.
NCBI Gene ID #:
2654026
NCBI Official Name:
SNVsMgp1 glycoprotein precursor
NCBI Official Symbol:
SNVsMgp1
NCBI Organism:
Sin Nombre virus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
N/A
Protein Accession #:
NP_941974
Protein GI Number:
38371724
Purification:
Sin Nombre virus glycoprotein 1 antibody is affinity chromatography purified via peptide column.
Research Area:
Infectious Disease
Swissprot #:
Q89905
User NOte:
Optimal dilutions for each application to be determined by the researcher.