ProSci

FLIP Peptide

Product Code:
 
PSI-1161P
Product Group:
 
Peptides
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
 

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CodeSizePrice
PSI-1161P-0.05mg0.05mg£166.00
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Further Information

Additional Names:
CASH, FLIP, MRIT, CLARP, FLAME, Casper, FLAME1, c-FLIP, FLAME-1, I-FLICE, c-FLIPL, c-FLIPR, c-FLIPS, CASP8AP1, CASH, CASP8 and FADD-like apoptosis regulator, Caspase homolog
Application Note:
FLIP peptide is used for blocking the activity of FLIP antibody.
Background References:
  • Irmler M, Thome M, Hahne M, Schneider P, Hofmann K, Steiner V, Bodmer JL, Schroter M, Burns K, Mattmann C, Rimoldi D, French LE, Tschopp J. Inhibition of death receptor signals by cellular FLIP. Nature 1997;388:190-195.
  • Zhang Y, Zhou L, Miller CA. A splicing variant of a death domain protein that is regulated by a mitogen-activated kinase is a substrate for c-Jun N-terminal kinase in the human central nervous system. Proc Natl Acad Sci U S A 1998;95:2586-2591
  • Brown TL and Howe PH. MADD is highly homologous to a Rab3 guanine-nucleotide exchange protein (Rab3-GEP). Curr Biol 1998;8:R191
Buffer:
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
Concentration:
200 ug/mL
NCBI Gene ID #:
8837
NCBI Official Name:
CASP8 and FADD-like apoptosis regulator
NCBI Official Symbol:
CFLAR
NCBI Organism:
Homo sapiens
Peptide aa Location:
18 amino acids near the carboxy terminus of human FLIP.
Physical State:
Liquid
Protein Accession #:
AAC51622
Protein GI Number:
2253679
Swissprot #:
O15519

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