ProSci

FECH Antibody

Product Code:
 
PSI-29-655
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
 
For short periods of storage (days) store at 4˚C. For longer periods of storage, store FECH antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
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Antibody used in IHC on Human Liver at 4.0-8.0 ug/ml.
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Antibody used in IHC on Human Liver at 4.0-8.0 ug/ml.

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PSI-29-655-100ul100ul£662.00
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Further Information

Additional Names:
FECH, EPP, FCE
Application Note:
FECH antibody can be used for detection of FECH by ELISA at 1:312500. FECH antibody can be used for detection of FECH by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
Ferrochelatase is localized to the mitochondrion where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Defects in ferrochelatase are associated with protoporphyria.Ferrochelatase is localized to the mitochondrion where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Defects in ferrochelatase are associated with protoporphyria. Two transcript variants encoding different isoforms have been found for this gene.Ferrochelatase is localized to the mitochondrion where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Defects in ferrochelatase are associated with protoporphyria. Two transcript variants encoding different isoforms have been found for this gene.
Background References:
  • Collin, C., (2005) Blood 106 (3), 1098-1104.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FECH.
NCBI Gene ID #:
2235
NCBI Official Name:
ferrochelatase
NCBI Official Symbol:
FECH
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
47 kDa
Protein Accession #:
NP_001012533
Protein GI Number:
60499025
Purification:
Antibody is purified by peptide affinity chromatography method.
Swissprot #:
Q8NAN0
User NOte:
Optimal dilutions for each application to be determined by the researcher.