Antibody Clonality:
Polyclonal
Application:
Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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Further Information
TRKB, trk-B, GP145-TrkB, BDNF/NT-3 growth factors receptor precursor, GP145-TrkB/GP95-TrkB, NTRK2, Trk-B
Western Blot: 1:500~1:1000
Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC γ1.
- Woronowicz A, et al. Glycobiology. 2007 Jan;17 (1): 10-24. Mojsilovic-Petrovic J, et al. J Neurosci. 2006 Sep 6;26 (36): 9250-63. Lewis MA, et al. Mol Pharmacol. 2006 Apr;69 (4): 1396-404. Cai D, et al. Physiol Genomics. 2006 Feb 14;24 (3): 191-7.
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
1 mg/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
TrkB (Ab-705) antibody was raised against a peptide sequence around aa.703~707 (T-D-Y -Y-R) derived from TrkB.
4915
neurotrophic tyrosine kinase, receptor, type 2
NTRK2
This antibody was raised against a peptide sequence around aa.703~707 (T-D-Y -Y-R) derived from TrkB
Liquid
PREDICTED MOLECULAR WEIGHT:
145 kDa
NP_001007098.1
55956790
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Neuroscience
This antibody detects endogenous levels of total TrkB protein.
Q16620