ProSci

PODXL Antibody

Product Code:
 
PSI-31-353
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
For short periods of storage (days) store at 4˚C. For longer periods of storage, store PODXL antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
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Antibody used in IHC on Human kidney at 5.0 ug/ml.
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Antibody used in IHC on Human kidney at 5.0 ug/ml.

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PSI-31-353-100ul100ul£662.00
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This product comes from: United States.
Typical lead time: 14-21 working days.
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Further Information

Additional Names:
PODXL, Gp200, MGC138240, PCLP, PC, PCLP-1
Application Note:
PODXL antibody can be used for detection of PODXL by ELISA at 1:312500. PODXL antibody can be used for detection of PODXL by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
PODXL is a member of the sialomucin protein family. PODXL was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.
Background References:
  • Qiu, D., (2008) Biochem. Biophys. Res. Commun. 369 (2), 735-740.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PODXL.
NCBI Gene ID #:
5420
NCBI Official Name:
podocalyxin-like
NCBI Official Symbol:
PODXL
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
56 kDa
Protein Accession #:
NP_001018121
Protein GI Number:
66277202
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Membrane ,Cancer
Swissprot #:
A6NHX8
User NOte:
Optimal dilutions for each application to be determined by the researcher.