ProSci

SWAP70 Antibody

Product Code:
 
PSI-30-175
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
For short periods of storage (days) store at 4˚C. For longer periods of storage, store SWAP70 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
1 / 1
Antibody used in WB on Human HepG2 at 5.0 ug/ml.
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Antibody used in WB on Human HepG2 at 5.0 ug/ml.

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PSI-30-175-100ul100ul£609.00
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Further Information

Additional Names:
SWAP70, FLJ39540, HSPC321, KIAA0640, SWAP-70
Application Note:
SWAP70 antibody can be used for detection of SWAP70 by ELISA at 1:62500. SWAP70 antibody can be used for detection of SWAP70 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. SWAP70 also mediates signaling of membrane ruffling. It regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion.
Background References:
  • Liu, J., (2007) J. Histochem. Cytochem. 55 (7), 701-708.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SWAP70.
NCBI Gene ID #:
23075
NCBI Official Name:
SWAP switching B-cell complex 70kDa subunit
NCBI Official Symbol:
SWAP70
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
69 kDa
Protein Accession #:
NP_055870
Protein GI Number:
93102364
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Immunology
Swissprot #:
Q9UH65
User NOte:
Optimal dilutions for each application to be determined by the researcher.