ProSci

ASPSCR1 Antibody

Product Code:
 
PSI-79-649
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store antibody at -20˚C for up to one year.
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Western blot analysis of lysed extracts from HL60 cells using ASPSCR1 Antibody.
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Western blot analysis of lysed extracts from HL60 cells using ASPSCR1 Antibody.

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CodeSizePrice
PSI-79-649-0.1mg0.1mg£481.00
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Further Information

Additional Names:
TUG, ASPL, ASPS, RCC17, UBXD9, UBXN9, ASPCR1, HSP27, HSP28, TUG
Application Note:
Western Blot: 1:500~1:1000
Background:
Tug (Tether containing UBX domain for GLUT4), also known as ASPL, ASPSCR1, RCC17, UBXD9, UBXN9, was first identified as a chromosomal translocation partner for TFE3 in patients with Alveolar soft part sarcoma and contains an UBX-like domain in its C-terminal region. Tug is found to tether GLUT4 in intracellular vesicles and to release GLUT4 for cell surface translocation upon insulin stimulation . Stable Tug depletion or expression of a dominant negative form stimulates GLUT4 redistribution.
Background References:
  • Ladanyi, M. et al. (2001) Oncogene 20, 48-57. Bogan, J. S. et al. (2003) Nature 425, 727-33. Yu, C. et al. (2007) J Biol Chem 282, 7710-22.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
ASPSCR1 antibody was raised against a peptide sequence around aa.303 ~307 (P-Q-Q-E-Q) derived from Human ASPSCR1.
NCBI Gene ID #:
79058
NCBI Official Name:
alveolar soft part sarcoma chromosome region, candidate 1
NCBI Official Symbol:
ASPSCR1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
70 - 75 kDa
Protein Accession #:
NP_076988.1
Protein GI Number:
13129078
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Other
SPECIFICITY:
This antibody detects endogenous levels of total ASPSCR1 protein.
Swissprot #:
Q9BZE9