ProSci

Smad2 Antibody

Product Code:
 
PSI-79-618
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Western Blot (WB)
Storage:
 
Store antibody at -20˚C for up to one year.
1 / 2
Western blot analysis of lysed extracts from HeLa cells using Smad2 (Ab-467).
2 / 2
Immunofluorescence staining of methanol-fixed HeLa cells using Smad2 (Ab-467).
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Western blot analysis of lysed extracts from HeLa cells using Smad2 (Ab-467).
Immunofluorescence staining of methanol-fixed HeLa cells using Smad2 (Ab-467).

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PSI-79-618-0.1mg0.1mg£481.00
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Further Information

Additional Names:
JV18, MADH2, MADR2, JV18-1, hMAD-2, hSMAD2, Mad-related protein 2
Application Note:
Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200
Background:
Transcriptional modulator activated by TGF-beta and activin type 1 receptor kinase. SMAD2 is a receptor-regulated SMAD (R-SMAD). May act as a tumor suppressor in colorectal carcinoma.
Background References:
  • Sang Gyun Kim et al. (2004) Mol Biol Cell. February; 15 (2): 420?434. Rebecca A. Randall et al. (2004) Mol Cell Biol. February; 24 (3): 1106?1121. Kimberly A Brown et al. (2004) Breast Cancer Res. ; 6 (3): R215?R231.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Smad2 (Ab-467) antibody was raised against a peptide sequence around aa. 463~467 (C-S-S-M-S) derived from Human Smad2.
NCBI Gene ID #:
4087
NCBI Official Name:
SMAD family member 2
NCBI Official Symbol:
SMAD2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
60 kDa
Protein Accession #:
NP_001003652.1
Protein GI Number:
51173730
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Other
SPECIFICITY:
This antibody detects endogenous level of total Smad2 protein.
Swissprot #:
Q15796