Antibody Clonality:
Polyclonal
Applications:- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.
1 / 2
2 / 2
❮❯No additional charges, what you see is what you pay! *
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available!
Contact us to find what you can save.
This product comes from:
United States.
Typical lead time:
14-21 working days.
Contact us for more accurate information.
- Further Information
- Documents
- Show All
Further Information
SRK, STD, TZK, STCD, ZAP-70, ERBB, ERBB1, HER1, 70 kDa zeta-associated protein, SRK, Syk-related tyrosine kinase, ZA70
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
ZAP70 is a 70-kD tyrosine phosphoprotein that associates with the ζ chain and undergoes tyrosine phosphorylation following TCR stimulation. The ZAP70 gene is expressed in T- and natural KILLER cells. Protein-Tyrosine Kinases (PTKs) play an integral role in T-cell activation. Stimulation of the T-cell antigen receptor results in tyrosine phosphorylation of a number of cellular substrates. One of these is the TCR-ζ chain, which can mediate the transduction of extracellular stimuli into cellular effector functions
- Chan AC, et al. (1995) EMBO J; 14 (11): 2499-2508Kong G, et al. (1996) Mol Cell Biol; 16 (9): 5026-5035Salomon AR, et al. (2003) Proc Natl Acad Sci U S A; 100 (2): 443-448
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
1 mg/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Zap-70 (Ab-493) antibody was raised against a peptide sequence around aa.491~495 (S-Y-Y-T-A) derived from Human ZAP70.
7535
zeta-chain (TCR) associated protein kinase 70kDa
ZAP70
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
70 kDa
NP_001070.2
31455611
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Other
This antibody detects endogenous level of total Zap-70 protein.
P43403