ProSci

LRRC8A Antibody

Product Code:
 
PSI-26-404
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
For short periods of storage (days) store at 4˚C. For longer periods of storage, store LRRC8A antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
1 / 1
Antibody used in WB on Human Jurkat 0.2-1 ug/ml.
❮❯

Antibody used in WB on Human Jurkat 0.2-1 ug/ml.

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PSI-26-404-100ul100ul£662.00
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Further Information

Additional Names:
LRRC8A, FLJ10337, KIAA1437, LRRC8, AGM5
Application Note:
LRRC8A antibody can be used for detection of LRRC8A by ELISA at 1:62500. LRRC8A antibody can be used for detection of LRRC8A by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
LRRC8A is a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. LRRC8A is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.
Background References:
  • Smits, G. (2004) Mol. Immunol. 41 (5), 561-562.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human LRRC8A.
NCBI Gene ID #:
56262
NCBI Official Name:
leucine rich repeat containing 8 family, member A
NCBI Official Symbol:
LRRC8A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
94 kDa
Protein Accession #:
NP_062540
Protein GI Number:
62241040
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Membrane
Swissprot #:
Q8IWT6
User NOte:
Optimal dilutions for each application to be determined by the researcher.