ProSci

FXYD5 Antibody

Product Code:
 
PSI-28-718
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
For short periods of storage (days) store at 4˚C. For longer periods of storage, store FXYD5 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
1 / 2
Antibody used in WB on Human Placenta at 0.625 ug/ml.
2 / 2
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Antibody used in WB on Human Placenta at 0.625 ug/ml.

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PSI-28-718-100ul100ul£609.00
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Further Information

Additional Names:
FXYD5, RIC, IWU1, KCT1, OIT2, DYSAD, HSPC113, PRO6241
Application Note:
FXYD5 antibody can be used for detection of FXYD5 by ELISA at 1:312500. FXYD5 antibody can be used for detection of FXYD5 by western blot at 0.625 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
FXYD5 is a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIon Channel (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIon Channel) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. This gene product, FXYD5, has not been characterized as a protein.
Background References:
  • Batistatou, A., et al., (2005) Br. J. Cancer 93 (12), 1382-1387.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FXYD5.
NCBI Gene ID #:
53827
NCBI Official Name:
FXYD domain containing ion transport regulator 5
NCBI Official Symbol:
FXYD5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
20 kDa, 19 kDa
Protein Accession #:
NP_659003
Protein GI Number:
47778938
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Membrane ,Cancer
Swissprot #:
Q96DB9
User NOte:
Optimal dilutions for each application to be determined by the researcher.