Further Information
ABCC1, ABC29, ABCC, DKFZp686N04233, DKFZp781G125, GS-X, MRP, MRP1
ABCC1 antibody can be used for detection of ABCC1 by ELISA at 1:62500. ABCC1 antibody can be used for detection of ABCC1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
ABCC1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternative splicing by exon deletion results in several splice variants but maintains the original open reading frame in all forms. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternative splicing by exon deletion results in several splice variants but maintains the original open reading frame in all forms.
- Nabekura, T., (2008) Biochem. Biophys. Res. Commun. 369 (2), 363-368.
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
batch dependent
Unconjugated
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ABCC1.
4363
ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
171 kDa
NP_004987
134142337
Antibody is purified by peptide affinity chromatography method.
Membrane ,Cancer ,Signal Transduction
P33527
Optimal dilutions for each application to be determined by the researcher.