Further Information
FZD4, EVR1, FEVR, FZD4S, Fz-4, FzE4, GPCR, MGC34390, Fz4, hFz4, CD344
FZD4 antibody can be used for detection of FZD4 by ELISA at 1:312500. FZD4 antibody can be used for detection of FZD4 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
FZD4 is a member of the frizzled family. Members of this family are seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
- Dufourcq, P., (2008) Am. J. Pathol. 172 (1), 37-49.
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
batch dependent
Unconjugated
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FZD4.
8322
frizzled class receptor 4
FZD4
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
60 kDa
NP_036325
22547161
Antibody is purified by peptide affinity chromatography method.
Membrane ,Cancer ,Signal Transduction
Q9ULV1
Optimal dilutions for each application to be determined by the researcher.