Further Information
EDA, ED1, ED1-A1, ED1-A2, EDA1, EDA2, HED, XHED, XLHED, HED1, ODT1, ECTD1, EDA-A1, EDA-A2, STHAGX1
EDA antibody can be used for detection of EDA by ELISA at 1:312500. EDA antibody can be used for detection of EDA by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
EDA is a type II membrane protein that can be cleaved by furin to produce a secreted form. It belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene.
- Zhao, J., (2008) Br. J. Dermatol. 158 (3), 614-617.
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
batch dependent
Unconjugated
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human EDA.
1896
ectodysplasin A
EDA
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
41 kDa
NP_001005609
54112101
Antibody is purified by peptide affinity chromatography method.
Membrane ,Cancer ,Signal Transduction ,Immunology
B7ZLU4
Optimal dilutions for each application to be determined by the researcher.