Antibody Clonality:
Polyclonal
Applications:- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store PDCD8 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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- Further Information
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Further Information
PDCD8, RP3-438D16.2, AIF, MGC111425, CMT2D, CMTX4, COWCK, NADMR, NAMSD, PDCD8, COXPD6
PDCD8 antibody can be used for detection of PDCD8 by ELISA at 1:62500. PDCD8 antibody can be used for detection of PDCD8 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
AIFM1 (PDCD8) is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, AIFM1 induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9.This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Three alternative transcripts encoding different isoforms have been identified for this gene.This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Three alternative transcripts encoding different isoforms have been identified for this gene.
- Delettre, C., (er) J. Biol. Chem. (2006) In press.
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
batch dependent
Unconjugated
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PDCD8.
9131
apoptosis-inducing factor, mitochondrion-associated, 1
AIFM1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
66 kDa, 67 kDa
NP_665811
22202629
Antibody is purified by peptide affinity chromatography method.
Transcription
O95831-3
Optimal dilutions for each application to be determined by the researcher.