Antibody Clonality:
Polyclonal
Application:
Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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Further Information
ATV, NBS, P95, NBS1, AT-V1, AT-V2, TCF5, PP9092,
Western Blot: 1:500~1:1000
Mutations in p95/NBS1 gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.
- Hsu HL, et al (2005) Oncogene; 24 (31): 4956-64. Falck J, et al. (2005) Nature; 434 (7033): 605-11. Buscemi G, et al. (2004) Oncogene; 23 (46): 7691-700. Beausoleil SA, et al. (2004) Proc Natl Acad Sci U S A; 101 (33): 12130-5.
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
1 mg/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
p95/NBS1 (Phospho-Ser343) antibody was raised against a peptide sequence around phosphorylation site of serine 343 (S-L-S (p) -Q-G) derived from Human p95/NBS1.
Phospho-Specific
4683
nibrin
NBN
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
95 kDa
NP_002476.2
33356172
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Phospho-Specific,Cell Cycle
This antibody detects endogenous level of p95/NBS1 only when phosphorylated at serine 343.
O60934