Further Information
JNKK, MEK4, MKK4, SEK1, SKK1, JNKK1, SERK1, MAPKK4, PRKMK4, SAPKK1, SAPKK-1, C9orf88, JNKK, MAP2K4, MAPK/ERK kinase 4, MAPKK 4
Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
Dual specificity kinase that activates the JUN kinases MAPK8 (JNK1) and MAPK9 (JNK2) as well as MAPK14 (p38) but not MAPK1 (ERK2) or MAPK3 (ERK1).
- Wang W, et al. (2002) Mol Cell Biol; 22 (10): 3389-403. Leung IW, et al. (2001) J Biol Chem; 276 (3): 1961-7.
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
1 mg/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
SEK1/MKK4 (Ab-261) antibody was raised against a peptide sequence around aa.259~263 (A-K-T-R-D) derived from Human SEK1/MKK4.
6416
mitogen-activated protein kinase kinase 4
MAP2K4
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
44 kDa
NP_003001.1
4506889
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Other
This antibody detects endogenous level of total SEK1/MKK4 protein.
P45985