Further Information
UBE2D3, E2(17)KB3, MGC43926, MGC5416, UBC4/5, UBCH5C
UBE2D3 antibody can be used for detection of UBE2D3 by ELISA at 1:1562500. UBE2D3 antibody can be used for detection of UBE2D3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D3 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Multiple spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.
- Hattori, H., (2007) Blood 110 (2), 640-650.
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
batch dependent
Unconjugated
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human UBE2D3.
7323
ubiquitin-conjugating enzyme E2D 3
UBE2D3
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
17 kDa
NP_003331
4507777
Antibody is purified by peptide affinity chromatography method.
Cancer ,Apoptosis ,Homeostasis
P61077
Optimal dilutions for each application to be determined by the researcher.