Further Information
ADAMTS18, ADAMTS21, KNO2, MMCAT
ADAMTS18 antibody can be used for detection of ADAMTS18 by ELISA at 1:12500. ADAMTS18 antibody can be used for detection of ADAMTS18 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
ADAMTS18 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein has a high sequence similarity to the protein encoded by gene ADAMTS16, another family member. It is thought to function as a tumor suppressor. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined. This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has a high sequence similarity to the protein encoded by gene ADAMTS16, another family member. It is thought to function as a tumor suppressor. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined.
- Nordgard, S.H., (er) Genes Chromosomes Cancer (2008) In press.
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
batch dependent
Unconjugated
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ADAMTS18.
170692
ADAM metallopeptidase with thrombospondin type 1 motif, 18
ADAMTS18
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
104 kDa
NP_955387
40806187
Antibody is purified by peptide affinity chromatography method.
Cancer ,Signal Transduction
Q8TE60
Optimal dilutions for each application to be determined by the researcher.