ProSci

MAK Antibody

Product Code:
 
PSI-25-754
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
For short periods of storage (days) store at 4˚C. For longer periods of storage, store MAK antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
1 / 3
Antibody used in WB on Human HeLa at 0.2-1 ug/ml.
2 / 3
3 / 3
Antibody used in IHC on Human A549 at 1:100.
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Antibody used in WB on Human HeLa at 0.2-1 ug/ml.
Antibody used in IHC on Human A549 at 1:100.

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PSI-25-754-100ul100ul£662.00
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Further Information

Additional Names:
MAK, dJ417M14.2, RP62
Application Note:
MAK antibody can be used for detection of MAK by ELISA at 1:312500. MAK antibody can be used for detection of MAK by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
MAK is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. It is expressed almost exclusively in the testis, primarily in germ cells. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. There is, however, a study of the mouse homolog that has identified high levels of expression in developing sensory epithelia so its function may be more generalized.The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. It is expressed almost exclusively in the testis, primarily in germ cells. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. There is, however, a study of the mouse homolog that has identified high levels of expression in developing sensory epithelia so its function may be more generalized.
Background References:
  • Fu, Z., (2006) Mol. Cell. Biol. 26 (22), 8639-8654.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MAK.
NCBI Gene ID #:
4117
NCBI Official Name:
male germ cell-associated kinase
NCBI Official Symbol:
MAK
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
70 kDa
Protein Accession #:
NP_005897
Protein GI Number:
11496279
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Cancer ,Signal Transduction
Swissprot #:
P20794
User NOte:
Optimal dilutions for each application to be determined by the researcher.