Antibody Clonality:
Polyclonal
Applications:- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.
1 / 2
2 / 2
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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Further Information
AMPK, AMPKa1, MAPTL, MTBT1, TAU,
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
Responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit.
- Hurley RL, et al. (2005) J Biol Chem. Aug 12; 280 (32): 29060-29066Woods A, et al. (2003) Curr Biol. Nov 11; 13 (22): 2004-2008Nielsen JN, et al. (2003) J Appl Physiol. Feb; 94 (2): 631-641Da Silva Xavier G, et al. (2000) Proc Natl Acad Sci U S A. Apr 11; 97 (8): 4023-4028.
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
1 mg/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
AMPKa1/AMPKa2 (Ab-174/172) antibody was raised against a peptide sequence around aa. 172~176/170~174 (L-R-T-S-C) derived from Human AMPKα1/AMPKα2.
5562 / 5563
protein kinase, AMP-activated, alpha 1 catalytic subunit / protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKAA1 PRKAA2
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
63 kDa
NP_006242.5 / NP_006243.2
94557301 / 46877068
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Other
This antibody detects endogenous level of total AMPKα1/AMPKα2 protein.
Q13131