ProSci

ALDOA Antibody

Product Code:
 
PSI-30-356
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
For short periods of storage (days) store at 4˚C. For longer periods of storage, store ALDOA antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
1 / 1
Antibody used in WB on Human HepG2 at 0.25 ug/ml.
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Antibody used in WB on Human HepG2 at 0.25 ug/ml.

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PSI-30-356-100ul100ul£609.00
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Further Information

Additional Names:
ALDOA, ALDA, MGC10942, MGC17716, MGC17767, GSD12, HEL-S-87p
Application Note:
ALDOA antibody can be used for detection of ALDOA by ELISA at 1:62500. ALDOA antibody can be used for detection of ALDOA by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
ALDOA is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia.This gene product, Aldolase A (fructose-bisphosphate aldolase) is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing of this gene results in multiple transcript variants which encode the same protein.
Background References:
  • Lu, J., (2008) Biochem. Biophys. Res. Commun. 369 (3), 948-952.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ALDOA.
NCBI Gene ID #:
226
NCBI Official Name:
aldolase A, fructose-bisphosphate
NCBI Official Symbol:
ALDOA
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
39 kDa
Protein Accession #:
NP_000025
Protein GI Number:
4557305
Purification:
Antibody is purified by protein A chromatography method.
Swissprot #:
P04075
User NOte:
Optimal dilutions for each application to be determined by the researcher.